KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF4
All Species:
26.97
Human Site:
S155
Identified Species:
39.56
UniProt:
O43172
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43172
NP_004688.2
522
58449
S155
T
K
K
D
D
E
K
S
K
K
S
K
E
E
Y
Chimpanzee
Pan troglodytes
XP_520198
559
62217
S192
T
K
K
D
D
E
K
S
K
K
S
K
E
E
Y
Rhesus Macaque
Macaca mulatta
XP_001102859
521
58408
S154
T
K
K
D
D
E
K
S
K
K
S
K
E
E
Y
Dog
Lupus familis
XP_532038
521
58332
S154
T
K
K
D
D
E
K
S
K
K
S
K
E
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAW6
521
58352
S154
T
K
K
D
D
E
K
S
K
K
S
K
E
E
Y
Rat
Rattus norvegicus
Q5BK30
415
45841
S58
V
E
P
L
I
T
A
S
R
T
K
Q
V
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518220
390
43930
T33
S
R
E
E
Y
Q
Q
T
W
Y
H
E
G
P
N
Chicken
Gallus gallus
Q5ZMA2
505
55116
V142
K
P
Q
A
G
L
I
V
P
Q
A
V
P
S
S
Frog
Xenopus laevis
Q5FWQ6
415
45899
S58
A
E
P
L
I
T
A
S
R
T
Q
Q
V
K
Q
Zebra Danio
Brachydanio rerio
Q1LV15
415
45916
S58
A
E
P
L
I
T
S
S
C
V
E
Q
V
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
K53
K
F
G
G
L
L
E
K
K
W
T
S
V
I
R
Honey Bee
Apis mellifera
XP_393186
525
59172
S148
H
E
E
E
E
K
P
S
H
P
I
E
R
D
T
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
L135
A
R
E
A
L
S
T
L
K
P
H
T
S
A
K
Sea Urchin
Strong. purpuratus
XP_795434
502
56264
A140
E
K
A
K
D
G
E
A
E
K
Q
T
T
W
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22212
554
61823
D174
L
V
K
D
H
E
E
D
V
T
P
K
E
E
V
Baker's Yeast
Sacchar. cerevisiae
P20053
465
52424
D108
V
D
E
E
D
D
E
D
F
F
T
P
A
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
99
99.2
N.A.
98.8
25.4
N.A.
71.2
21
24.1
24.3
N.A.
22.2
58.2
22
62
Protein Similarity:
100
93.1
99.2
99.6
N.A.
99.4
40.6
N.A.
73.3
41.3
41.3
41.5
N.A.
39.6
72.9
40.6
77
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
0
0
6.6
6.6
N.A.
6.6
6.6
6.6
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
53.3
20
33.3
26.6
N.A.
20
53.3
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
31.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.7
51.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
7
13
0
0
13
7
0
0
7
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
0
38
44
7
0
13
0
0
0
0
0
7
0
% D
% Glu:
7
25
25
19
7
38
25
0
7
0
7
13
38
38
0
% E
% Phe:
0
7
0
0
0
0
0
0
7
7
0
0
0
0
0
% F
% Gly:
0
0
7
7
7
7
0
0
0
0
0
0
7
0
0
% G
% His:
7
0
0
0
7
0
0
0
7
0
13
0
0
0
0
% H
% Ile:
0
0
0
0
19
0
7
0
0
0
7
0
0
7
0
% I
% Lys:
13
38
38
7
0
7
32
7
44
38
7
38
0
13
7
% K
% Leu:
7
0
0
19
13
13
0
7
0
0
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
7
19
0
0
0
7
0
7
13
7
7
7
7
0
% P
% Gln:
0
0
7
0
0
7
7
0
0
7
13
19
0
0
7
% Q
% Arg:
0
13
0
0
0
0
0
0
13
0
0
0
7
7
7
% R
% Ser:
7
0
0
0
0
7
7
57
0
0
32
7
7
7
13
% S
% Thr:
32
0
0
0
0
19
7
7
0
19
13
13
7
7
7
% T
% Val:
13
7
0
0
0
0
0
7
7
7
0
7
25
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
7
7
0
0
0
7
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
38
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _